Anti Cancer Products
Zoldria-zoledronic Acid
Zoldria contains zoledronic acid and belongs to a class of medications called bisphosphonates.
Indication
Zoldria is used to treat osteoporosis in women and men. Zoldria is also used to treat paget's disease of bone. zoldria may be used to treat bone disease in patients who have cancer.
Mechanism of Action
Zoldria works by decreasing the breakdown of the bone and increasing the bone density (thickness). This reduces the amount of calcium that is released into the blood from bones and helps to lower your blood calcium level.
Supplied as:
Zoldria is available as 4mg single dose vial.
Overdose
Symptoms of overdose associated with zoldria may include dizziness; decreased urination; fast, pounding or irregular heartbeat; mental or mood changes; muscle cramps; numbness or tingling, (especially around the mouth), fever, muscle weakness, depression, difficulty walking, seizures, confusion, shortness of breath, sudden tightening of muscles, numbness, or tingling in fingers or toes; double vision & difficulty in speaking.
Precautions & Warnings
Zoldria should not be taken without consulting your doctor if you have kidney disease, liver disease, cardiac disease, an electrolyte imbalance, asthma, hypocalcemia, hypoparathyroidism, or if you had undergone thyroid or parathyroid surgery.
Do not take zoldria if you are sensitive to aspirin because it may increase the risk of bronchoconstriction.
Do not take zoldria without consulting your doctor if you are pregnant. It is not known whether zoldria passes into breast milk. Do not take zoldria without consulting your doctor if you are breast feeding a baby.
Drug Interactions
The following drugs may interact with zoldria:
The side effects associated with zoldria are severe allergic reactions such as nausea, vomiting, irritation or swelling at the injection site, fever, chills , rash, itching, dizziness, headache, weakness, tiredness, trouble sleeping, shortness of breath, burning or painful urination, mood changes (e. G. , agitation, anxiety, confusion), swelling of the legs or mouth, vision problems (conjunctivitis), seizures, stupor, ankles, or hands, jaw tightness, electrolyte disturbances, anaemia, dyspnoea, chest pain, cough, excessive sweating, hypertension, and muscle and joint aches or pains etc.
Note: Zoldria is a prescription drug and should be used under proper medical guidance and advice.
Indication
Zoldria is used to treat osteoporosis in women and men. Zoldria is also used to treat paget's disease of bone. zoldria may be used to treat bone disease in patients who have cancer.
Mechanism of Action
Zoldria works by decreasing the breakdown of the bone and increasing the bone density (thickness). This reduces the amount of calcium that is released into the blood from bones and helps to lower your blood calcium level.
Supplied as:
Zoldria is available as 4mg single dose vial.
Overdose
Symptoms of overdose associated with zoldria may include dizziness; decreased urination; fast, pounding or irregular heartbeat; mental or mood changes; muscle cramps; numbness or tingling, (especially around the mouth), fever, muscle weakness, depression, difficulty walking, seizures, confusion, shortness of breath, sudden tightening of muscles, numbness, or tingling in fingers or toes; double vision & difficulty in speaking.
Precautions & Warnings
Zoldria should not be taken without consulting your doctor if you have kidney disease, liver disease, cardiac disease, an electrolyte imbalance, asthma, hypocalcemia, hypoparathyroidism, or if you had undergone thyroid or parathyroid surgery.
Do not take zoldria if you are sensitive to aspirin because it may increase the risk of bronchoconstriction.
Do not take zoldria without consulting your doctor if you are pregnant. It is not known whether zoldria passes into breast milk. Do not take zoldria without consulting your doctor if you are breast feeding a baby.
Drug Interactions
The following drugs may interact with zoldria:
- The risk of zoldria side effects may be increased by loop diuretics (bumetanide or furosemide), and aminoglycoside antibiotics (gentamicin, tobramycin) because they may lead to hypocalcaemia.
- The risk of zoldria side effects may be increased by mineral supplements (calcium, magnesium, or phosphorus).
- Serious risk of renal dysfunction may occur with nephrotoxic agents.
The side effects associated with zoldria are severe allergic reactions such as nausea, vomiting, irritation or swelling at the injection site, fever, chills , rash, itching, dizziness, headache, weakness, tiredness, trouble sleeping, shortness of breath, burning or painful urination, mood changes (e. G. , agitation, anxiety, confusion), swelling of the legs or mouth, vision problems (conjunctivitis), seizures, stupor, ankles, or hands, jaw tightness, electrolyte disturbances, anaemia, dyspnoea, chest pain, cough, excessive sweating, hypertension, and muscle and joint aches or pains etc.
Note: Zoldria is a prescription drug and should be used under proper medical guidance and advice.